Pablo Blazquez Lab
Medicine, Otolaryngology Washington University in St. Louis St. Louis, MO


Research Interests:

We study how the central nervous system processes sensory information to generate motor behaviours, and how this sensory-motor processing changes through learning. Currently we study how visual and vestibular information is transformed into compensatory eye movements. Our areas of interest
are the cerebellum and the brainstem. We are especially interested in the role of the different classes of neurons in the cerebellar cortex (e.g. Purkinje, Basket, Stellate, and Golgi cells) during oculomotor behaviors such as saccade and pursuit eye movements. We also study the role of the cerebellum-brainstem loop in the acquisition and consolidation process leading to the formation of new motor memories. Our model system to study motor learning is the vestibulo-ocular reflex.
Our experimental approach consist of studying the response of individiual neurons in the cerebellum and brainstem using single and multiunit recordings, pharmacology and histochemistry. Computational methods are also employed to better understand the role of specific elements of this circuit.

Research Group Page: Join to see more...